Research grants

Research grants are for projects of up to three years duration and up to £250,000, which covers everything from laboratory chemicals to salaries.

Pearse Keane looking into a microscope

Using Artificial Intelligence to predict AMD progression

Using a new artificial intelligence programme to understand the development of age-related macular degeneration (AMD).

Research Syringe

Switching off the genes that cause Best disease

Researching using a new gene editing technique to turn off the faulty gene that causes vision loss in Best disease.

Elderly woman leaning into eye examination machine.

An implantable eye lens for macular disease

Magnifying intraocular lenses can be given to patients with macular disease. This will be the first trial to see if they help.

A blood test

Creating a blood test to detect early AMD

Research is looking into a protein found in high levels in retinal cells of age-related macular disease patients. This protein could be used for treatment or diagnosis.

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How do ageing mitochondria work and communicate differently?

Looking at how mitochondria age to better understand the damage and changes that can occur with AMD, and how the damage could be stopped or reversed.

Couple looking at tablet

A virtual visually impaired rehabilitation assistant

This project is looking to create a ‘chat-bot’ to help answer patients’ questions about their macular disease or living with sight loss.

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Investigating early onset macular degeneration

Research to better understand early onset macular degeneration, and how it may provide insight into causes and treatment of age-related macular degeneration.

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New treatment option for wet AMD

Looking at a new protein for treating those with wet AMD who do not respond to anti-vascular endothelial growth factor (anti-VEGF) drugs.

DNA strands

Turning off faulty genes to treat macular dystrophy

New research using antisense oligonucleotide gene therapy to treat Doyne honeycomb dystrophy, a dominant genetic macular disease.

Technology graphics

Using data science to diagnose AMD sooner and detect change over time

Using data from thousands of patients. Researchers want to better understand the factors involved in the development of age-related macular degeneration (AMD).

Person reading a tablet

Using technology to aid functional vision

Creating a new application to help those with central vision loss be able to use their smartphones and tablets better, quicker and easier.

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Helping keep mitochondria healthy to keep macula cells alive

Investigating molecules involved in energy production and inflammation to see whether they can slow or stop damage to cells of the macula.

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Manchester Eye Tissue Repository Genome-Transcriptome Project

Investigating the gene changes that are responsible for macular dystrophies to improve genetic diagnosis and find new treatment options

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Creating a wet AMD drug using flower compounds

Creating and testing compounds found in rare flowers, in the hope of finding a new drug for wet AMD for people that don’t respond to current treatments.

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Understanding ABCA4 and predicting the future

This research is looking into why changes in the ABCA4 gene can cause macular dystrophies in some people, but others with these same changes remain healthy.

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Improving support services for teenagers with macular disease

This research project aims to create an integrated support package for teenagers with macular disease to improve wellbeing and mental health.

OCT scan

Investigating factors involved in rate of AMD progression

This research study will look at the genetic factors and structural changes that might determine who will develop late AMD faster, to better understand risk of progression.

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Testing therapies to reduce severity of visual hallucinations

Research trial comparing therapies to reduce impact and severity of visual hallucinations caused by Charles Bonnet Syndrome.

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Protecting damaged blood vessels in the back of the eye

This research aims to understand why blood vessels in the macular get damaged and how to stop it, in hope of finding new treatments for dry age-related macular degeneration (AMD).

RPE cells under a microscope

Understanding new stress response pathway involved in AMD

This research project aims to investigate a new pathway that reduces stress in the macular cells, to understand why it is reduced in age-related macular degeneration (AMD) and how this reduction may damage the macular.