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Research participant database
Get involved in research
There are many clinical trials and research studies looking at new treatments and ultimately trying to find a cure for macular disease. We are often approached by researchers to help find people willing to take part. Involvement can range from providing feedback on new developments, to undergoing treatment as part of a clinical trial.
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Research
Interested in the research we are funding with your generous donations?
How we’re finding a cure
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The vision of the Macular Society is to end macular disease through funding world-class medical research.
How we're improving life through research
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As well as medical research, the Macular Society funds research to help those living with macular disease now. For example, projects on the eccentric viewing technique have helped the Society to train and support those with macular disease to use their remaining vision most effectively.
Our achievements so far
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The vision of the Macular Society is to end macular disease through funding world-class medical research. Everything we fund is aimed at improving the treatment for or quality of life of patients with macular disease.
Action Against AMD (AAAMD) and the INSIGHT Hub
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Action Against AMD (AAAMD) is a partner of INSIGHT, one of seven ‘digital hubs’ funded by the government through Health Data Research UK, to create a UK-wide system for the safe and responsible use of health-related data on a large scale. The HDR Hub for Eye Health partnership includes experts from a range of backgrounds, including academia and pharmaceutical companies.
Our research projects
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Since 1987 the Macular Society has invested around £10 million in over 100 research projects. Each year we invite applications for research grants, PhD studentships and seedcorn grants which are assessed by our Research Committee.
Folding correction for Stargardt disease
Professor Mike Cheetham, UCL, Institute of Ophthalmology - £250,000
Stargardt disease is often caused by mutations in a gene called ABCA4. Mutations cause the ABCA4 protein produced to fold incorrectly and be removed from the cell. Without any ABCA4 protein the macula becomes damaged, which causes vision loss. This project aims to fix the misfolding, to restore ABCA4 in the cells, and therefore maintain a healthy macula and stop vision loss.
Finding early AMD changes using eye scans
Dr Ruth Hogg, Queen's University Belfast - £249,941
This project uses long-term follow-up of retinal scans from the Northern Ireland Cohort of the Longitudinal study of Ageing (NICOLA), to understand what changes in eye scans may be early signs of age-related macular degeneration (AMD).
Maintaining the health of the blood vessels in the macula
Professor Majlinda Lako, Newcastle University - £249,998
This project is aiming to understanding how the cells that make up the blood vessels in the macula may become damaged in early age-related macular degeneration (AMD). Following this, the goal is to find drug targets that can maintain blood vessel health to prevent or slow AMD progression.